Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Half life of hydroxychloroquine sulfate What is the highest doesagewith plaquenil How to cleanse body from plaquenil toxicity Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Plaquenil is indicated for the treatment of uncomplicated malaria due to P. falciparum, P. malariae, P. ovale, and P. vivax. Plaquenil is indicated for the prophylaxis of malaria in geographic areas where chloroquine resistance is not reported. Limitations of Use in Malaria Approach Considerations. Withdrawal of the medication and shifting to another form of treatment is the standard of care. No diet or medical therapy has been proven effective to prevent, treat, or reduce risk of retinal toxicity. Coordination with the rheumatologist or the dermatologist may be warranted for comprehensive care of the patient. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil retinopathy treatment Chloroquine retinopathy - Wikipedia, Plaquenil - FDA prescribing information, side effects and uses Does plaquenil cause low white blood cell countDeschloroquine used on chloroquine resistant parasitesPlaquenil and bursitis Research into the wide-ranging effects of hydroxychloroquine has revealed many important benefits in the treatment of lupus; it must be noted that these benefits may be less effective in people who smoke Arthritis Care & Research 2010; 3–400. Benefits include Decrease in the number of disease flares. Drug spotlight on hydroxychloroquine Lupus Foundation of.. Chloroquine and Hydroxychloroquine Toxicity Treatment.. Hydroxychloroquine Plaquenil Toxicity and.. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. The most common side effect associated with its use is retinal toxicity, which may be irreversible. Malaria. PLAQUENIL is indicated for the treatment of uncomplicated malaria due to P. falciparum, P. malariae, P. ovale, and P. vivax. PLAQUENIL is indicated for the prophylaxis of malaria in geographic areas where chloroquine resistance is not reported. Daily treatment with hydroxychloroquine, particularly when weight-based dosing is used, has been accepted as a major risk factor for hydroxychloroquine retinopathy Tables 1,2; however, the type of weight measurement used in these calculations IBW versus ABW is a matter of contention.