One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil urticaria treatment Hydroxychloroquine is it water pill Apr 10, 2019 Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Aug 29, 2014 The side effect that is of greatest concern is retinal toxicity. Retinal toxicity of Plaquenil may manifest itself with subtle disturbances of the retinal pigment epithelium which may eventually lead to complete destruction of the macula in the form of bull’s-eye maculopathy. Hydroxychloroquine Plaquenil is a disease-modifying antirheumatic drug that is commonly used to reduce arthritic pain and swelling. Signs and symptoms. “The association of Plaquenil therapy with macular toxicity is well established,” said Michael F. Marmor, MD, at the Byers Eye Institute at Stanford University. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Macular thinning plaquenil Hydroxychloroquine-Induced Retinal Toxicity - American., The Risk of Retinal Toxicity with Plaquenil Plaquenil pill dosageChloroquine alcohol useHydroxychloroquine dose based upon weight and renal functionChloroquine and primaquine doseHydroxychloroquine arthritis mechanism Feb 20, 2018 Focus on Eyes Long-term Plaquenil intake can affect your vision. Taking high doses or long-term treatment of Plaquenil, an anti-malaria drug used to treat lupus, can lead to vision problems. Focus on Eyes Long-term Plaquenil intake can affect your vision. Drug Toxicity to the Retina and Optic Nerve Are You Missing.. Hydroxychloroquine And Chloroquine Screening 2016 AAO.. Sep 13, 2019 Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Epiretinal membranes are a thin, almost transparent layer of fibrous cellular material that forms as a ‘film’ over the macula at the back of your eye, making it harder for you to see. It is a condition that is often confused with macular degeneration. Peripapillary retinal nerve fiber layer thinning was consistently seen in patients who presented with retinal lesions compatible with antimalarial toxicity. - Selective thinning of the inner retina in the 7 × 7 mm posterior pole was observed in those without clinically-apparent fundus changes.