Also had to have an occupational health meeting today for my job as not worked for 6 months now and hoping they make me redundant as i can't work as a waitress with ra due to pain and flares in my opinion. (others may do) and i then can get benefits till i find a job i can do with the ra(i am not doing this just for benefits, i hope people understand that) I have now been on Plaq for just over three years and MTX for just under three years. Does hydroxychloroquine affect the kidneys Can you donate blood if you take plaquenil May 07, 2019 ANSWER. Rheumatrex methotrexate is a chemotherapy drug used to suppress the immune system. Its use is becoming increasingly popular for skin disease, arthritis, and other non-life-threatening forms of disease that have not responded to medications such as hydroxychloroquine or low doses of prednisone. From Lupus Overview WebMD Medical Reference. Sorry to hear that you are having a lot of pain with your RA. I have lupus which mainly affects my joints and skin. I have been taking hydroxychloroquine which is the generic of plaquenil for the past three years. My rheumy recently added Imuran instead of methotrexate. Plaquenil hydroxychloroquine takes up to 3 months to begin working. Lupus and Plaquenil research. While Plaquenil was not created with the explicit purpose of helping people minimize the disease activity of lupus, a number of clinical trials have been conducted to examine the clinical impact of the medication. My Rheumy suggested MTX and told me it would be months before we knew for sure it would work. The combination works well for me-though I also take a NSAID. I started feeling better about a month after starting plaq-I was also on prednisone at the time-but couldn't get all the way well. Methotrexate and plaquenil for lupus Treating Lupus with Anti-Malarial Drugs Johns Hopkins., Which would you pick and why? - Plaquenil or Methotrexate Cost for plaquenilPlaquenil davisPlaquenil retinal toxicity screeningHydroxychloroquine stomach ulcer He was treated instead with low-dose oral methotrexate. Comment. Ultraviolet light is contra-indicated for patients with lupus, and prednisone is relatively contra-indicated for psoriasis. This is a case where Plaquenil likely triggered new-onset psoriasis in a patient who was genetically susceptible. Psoriasis Associated with Plaquenil Hydroxychloroquine.. Plaquenil Hydroxychloroquine for Lupus - LupusCorner. Lupus remission Lupus Foundation of America. Lupus & methotrexate research. While lupus is not specifically approved for lupus, there have been a large number of studies that intend to measure the effectiveness of the drug for people with lupus. Some studies are quite specific, finding benefit of methotrexate for people with cutaneous lupus, antimalarial-resistant lupus arthritis, and. I know Plaquenil has helped me a ton, because I tried going off of it once to see if I really needed it. The first two weeks weren't bad, as Plaquenil has a high half-life and there was still some Plaquenil in my body. After that, my Lupus got progressively worse until I gave up and re-started the Plaquenil after 6 weeks of being off it. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Taking methotrexate with hydroxychloroquine has.