It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Plaquenil red spots on chest Average weight loss on plaquenil Plaquenil and sarcoidosis Taking plaquenil with imuran Cornea verticillata also called vortex keratopathy, whorl keratopathy, or Fleischer vortex describes a whorl-like pattern of golden brown or gray opacities in the cornea. It is termed cornea verticillata from the Latin noun “verticillus,” meaning “whorl”. Hydroxychloroquine Plaquenil is an older DMARD sometimes still used for mild RA. It may work by interrupting signaling among cells. It’s one of the best tolerated DMARDs. Side effects are usually mild and may include nausea and diarrhea. Taking the drug with food may help. Changes to the skin are less common. Drug-induced corneal keratopathy is usually asymptomatic, and the changes rarely impair vision. The presence of keratopathy is not an indication for cessation of therapy; however, with drugs also known to cause retinal or optic nerve toxicity, regular observation and testing is necessary to reduce the risk of visual acuity loss. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Plaquenil whorl keratopathy COPE Disclosures Plaquenil Toxicity Update, RA 認識 免疫調節藥 - Hydroxychloroquine HCQ -. Vitamin c and plaquenilWhat antihistamines can be taken with plaquenil Apr 15, 2018 Ocular side effects of amiodarone include corneal verticillata or whorl-like keratopathy, which occur in 70% to 100% of patients. This keratopathy is related to the dose and duration of treatment, generally appears after at least one month of therapy and will resolve upon discontinuation of the medication. Know Your Systemic Meds The Top 10 to Track. Drug-induced corneal epithelial changes - ScienceDirect. Chloroquine and Hydroxychloroquine Toxicity Clinical Presentation. Chloroquine toxicity is characterized by whorl-like corneal epithelial deposits. Etiology Medications of the chloroquine family, including chloroquine Nivaquine, Avloclor, hydroxychloroquine Plaquenil, and amodiaquine, have been associated with keratopathy Srinivasan et al. 2011. Plaquenil hydroxychloroquine is an anti-malarial medication used to effectively treat rheumatoid arthritis and autoimmune conditions such as systemic lupus erythematosus and Sjögren’s Syndrome. Plaquenil is a drug that is stored in high concentrations throughout the body and is very slowly eliminated from the body. Hydroxychloroquine Keratopathy - Example #1. Hydroxychloroquine rarely can be seen as deposits in the basal epithelium of the cornea as shown in this image white arrows. This occurs commonly in patients taking chloroquine, but rarely in patients taking hydroxychloroquine. There is no relationship of this finding to the presence of.