It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Ocular toxicity plaquenil Plaquenil retinal toxicity cumulative dose calculator How long to treat patients with Lyme remains an issue of controversy. With traditional antibiotic therapy, lasting 2-4 weeks, 10-20% of patients will have ongoing symptoms including fatigue, joint. Individuals with neurologic Lyme disease, cardiac Lyme disease, or Lyme arthritis that hasn’t responded well to oral antibiotic treatment will often be given intravenous ceftriaxone. Ceftriaxone has excellent penetration of the blood-brain barrier and is one of the most effective drugs for Lyme disease. I've been diagnosed with Lyme disease, Q fever, rickettsia and I've been battling this for years. I have unbearable joint pain and syncopal episodes. I am a nurse. I have to say that the best I feel is on Plaquenil and doxycycline, with steroids occasionally. I have a flare. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Plaquenil for lyme Tick Bite Prophylaxis Tick-borne Diseases Ticks CDC, Treatment Options Lyme Disease Plaquenil generic namePlaquenil pulmonary toxicityChloroquine and quinine are commonly used to treatHydroxychloroquine & cholesterol-lowering medicationLichen planus chloroquine See Biofilms Lyme Disease Gated Communities for more information about biofilms and treatments. Macrolide plus Quinine Derivative plus Azole. Azithromycin Zithromax 500 mg 1 pill 1 time a day, hydroxychloroquine Plaquenil 200 mg 1 pill 2 times a day, and metronidazole Flagyl 500 mg 1 pill 2 or 3 times a day. Key Points A Lyme Disease Antibiotic Guide - Treat Lyme. LymeMD Plaquenil alone?. Question about Plaquenil - Lyme Disease. I am also making and drinking lyme tea made from a decoction I make of sarsaparilla, red root, cat’s claw and Japanese knotweed, three times a day. Should I also be taking plaquenil to kill the encysted form of the spirochete? Thank you. Jul 05, 2010 Hello, This is my first post. I was switched to a different anti-biotic regimen almost four weeks ago to treat chronic Lyme disease neuroborreliosis clarithromycin and hydroxychloroquine. I was just prescribed plaquenil to treat the cyst form of lyme. The usage of the drug says it is to suppress the immune system in the treatment of lupus. Why would you want to do this if you have lyme. I thought steriods and drugs that suppress the immune system make treatment much slower. I am reluctant to take it.