Please review the following URL and make sure that it is spelled correctly. An ANA test is a blood test that screens for anti-nuclear antibodies, or antibodies against DNA, which is the genetic material within the nucleus of every cell. Azathioprine and plaquenil Can you take plaquenil and ibuprofen Ana Definition An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. I was on plaquenil and prednisone, and my last ANA was also negative. I am convinced it is from the medicine. I am convinced it is from the medicine. My Dr. also sais it usually does not turn negative. These tests are crazy, right? You really do not have negative lupus tests. Only your ANA is negative. Your complement is low — must be characteristic of lupus specifically because my normal complement biases my doctor against lupus — and you have anti dsdna. These tests are diagnostic. People without SLE or another autoimmune disease usually have a low ANA titer, while a person with SLE will have a high one. This test is carried out using one of two assays, and the results are recorded as an antibody titer, which indicates the concentration of anti-nuclear antibodies in the bloodstream. Negative ana with plaquenil Positive then negative ANA test lupus, Lupus Board Index can negative ana turn positive Sjogren's hydroxychloroquine 44 Yes, the ANA levels can fluctuate and even be negative. A negative ANA doesn't rule out lupus, nor does a positive ANA confirm lupus. I know that sound contridictory, but a lupus dx comes from the symptoms. An elevated ANA is one of the 11 criteria for a lupus dx. Can ANA go away & Lupus Stay? - Lupus - MedHelp. Lupus panel and kidney question Can Plaquenil. - LUPUS UK. ANA negative lupus DailyStrength. Hi I am 30 years old and was diagnosed with fibromyalgia when I was 19. I too had positive.negative.positive ANA levels. Finally 2 years ago they did more than just the ANA and i do have lupus. I am just starting Plaquenil for the lupus. An ANA test will be positive 95 percent of the time when a person has lupus, so there are cases where a person has lupus and will have negative ANA testing. Likewise, a normal, healthy person who doesn’t have lupus or any other autoimmune disease can have a positive ANA. However, the ANA has been tested a few times and it's always negative. I'm 32, I have arthritis in my back which is said not to be associated with Lupus. I also have arthritis in fingers and wrists, pain in ankles and feet, and a deep aching pain in my hips.