I've been taking Plaquenil since February and have not had any flashes. I never had them associated with plaquenil, but I think I might remember someone else asking a similar question here at some time about plaquenil and hot flashes. You could either call your pharmacist or check the list of side effects they list when you pick up your next script . Hot flashes can come from Lupus itself..I don't remember if that is a direct cause or if its the lupus playing with hormones that makes then happen. Diagnosis code for plaquenil eye exam Chloroquine for malaria prophylaxis I have recently been diagnosed with SLE which is affecting my brain and CNS along with many other symptoms. I am very tired, nauseated, light headed, have ringing in my ears, and have noticed lately am having a lot of hot flashes or at least that is what I call them I get a hot feeling all over expecially in my face, face turns red, sometimes start feeling bad all over. StacyLee, I'm not sure about plaquenil and hot flashes. I never had them associated with plaquenil, but I think I might remember someone else asking a similar question here at some time about plaquenil and hot flashes. you could either call your pharmacist or check the list of side effects they list when you pick up your next script. May 07, 2012 Plaquenil Withdrawal Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor’s instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. I'd probably ask my rheumy about them next time I'm in if I were you. I had LOTS of hot flashes before my lupus became more controlled. Plaquenil hot flashes Temperature regulation hot flashes - Sjogren's symptom, or., Hot Flashes - Benefits of plaquenil for sjogren& 39Sulfasalazine and hydroxychloroquine side effectsAvoid sun with plaquenil Excessive sweating, hot flashes, or extreme body temperature fluctuations are a frequent challenge for MyLupusTeam members. They can be a side effect of medications, a symptom of menopause, a consequence of lupus’ impact on the nervous system and hormones, or another condition. Excessive Sweating and Lupus MyLupusTeam. Plaquenil Withdrawal – Life As An Anomaly. Wild Yam Uses, Side Effects, Interactions, Dosage, and Warning. Hi all- I've been on Plaquenil 400 mg daily for just about two months now. Shortly after starting I noticed a marked increase in the number of hot flashes/night sweats and anything at any time can irritate the heck out of me. Hot flashes, or as I call 'em "Power Surges" from plaquenil. Could be. I take lots a meds besides plaquenil. I had my doc do a blood test to see if I was starting menapause because I have power surges all the time. It was negative, so its one of the meds. Systemic lupus erythematosus lupus is an autoimmune disease with symptoms and outcomes that can vary greatly, from mild joint and skin problems to life-threatening conditions affecting the heart, kidneys and/or nervous system.