I can say that I am not having pain like I used to, and I am so grateful for that! I don't know if this is just the RA in full swing, or if it is a side effect of the Plaquenil. I have been running a low-grade fever (around 99.8) for about a week and a half now. Hydroxychloroquine and white spots on skin Hydroxychloroquine sulfate tablets side effects Does plaquenil have lifetime effects Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Jun 21, 2015 Hydroxychloroquine Plaquenil and generics can itself cause fatigue in some users, it can interrupt sleep patterns especially by causing more vivid dreams which in turn makes one more tired. The drug can also lower blood counts red cell, white cells and others too which in turn can cause fatigue. Hydroxychloroquine is the immunomodulatory drug most frequently used for primary Sjögren syndrome, 7 usually prescribed for patients with fatigue, arthralgia, and myalgia 8-10 rather than severe systemic manifestations. The latter symptoms are treated with corticosteroids and azathioprine, cyclophosphamide, mycophenolate mofetil, or rituximab. My normal body temperature is low, around 97.5, so I don't know if 99.8 would be considered a fever. It comes & goes and I can tell when it is up because I feel hot. Plaquenil et fatigue Hydroxychloroquine Plaquenil Success, Reviews and Side Effects, Is lethargy and tiredness a side effect of hydroxychloroquine? Can you get pregnant on plaquenil Plaquenil and Flatulence - from FDA reports Summary Flatulence is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years, also take medication Folic Acid, and have Arthritis. Will you have Flatulence with Plaquenil - eHealthMe. Hydroxychloroquine for Sjögren Syndrome Symptoms - The JAMA Network. Plaquenil for fatigue and pain DailyStrength. Plaquenil and Fatigue - from FDA reports Summary Fatigue is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Pain. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Fatigue is so frustrating for patients, but we don’t know much about it,” says Maria Dall’Era, MD, director of the Lupus Clinic and Rheumatology Clinical Research Center at the University.