It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine in chikungunya Plaquenil et alcool While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications. Before using hydroxychloroquine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions certain heart problems heart failure, slow heartbeat, QT. End stage hydroxychloroquine toxicity leads to widespread RPE and retinal atrophy with a loss of central vision, peripheral vision, and night vision. Recent studies have shown that patients of Asian descent develop initial damage in a more peripheral extramacular distribution near the arcades, most frequently in the inferotemporal region with corresponding superonasal field defects. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine eye problems Hydroxychloroquine toxicity - EyeWiki, Hydroxychloroquine Oral Uses, Side Effects, Interactions. HydroxychloroquinPlaquenil ophtalmo Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. PATIENT FACT SHEET Hydroxychloroquine Plaquenil. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble. I have only been taking Hydroxychloroquine for just over a year and have had no problems. I told the rheumatologist that I had early stages macular degeneration but they said it was not a problem. Recently i have had eye problems, my last eye test was January, so I went back to the optician who sent me to eye casualty. The most common place for Hydroxychloroquine to cause a problem is in a ring of the macula surrounding the fovea which is demonstated in the visual field test you can see in the picture above. The black areas are the areas the patinet couldn't see well.