As the media has discussed, Sjogren's is an autoimmune disease that attacks the tear and salivary glands and generally results in widespread dryness in the body. In addition to dry eyes and mouth, this can result in difficulty breathing and problems with digestive and bowel function. Plaquenil and allergies Buy plaquenil 200mg Jun 11, 2013 For many patients with Sjogren's, Plaquenil hydroxychloroquine has long been the go to drug that their doctors prescribe. It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the immune system. User Reviews for Plaquenil to treat Sjogren's Syndrome. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Sometimes that is how Sjogren's works. Symptoms seem to disappear for a few days and reappear. Plaquenil eventually helped my joint pain. The continued fatigue and other symptoms are related to my mctd so I am not the perfect judge for this. Treatment includes artificial tears and saliva and, in more severe cases, immune blockers such as prednisone, Plaquenil and even the cancer medication Methotrexate. As with most autoimmune illnesses, it is much more common in women than men. Does plaquenil help sjogren's syndrome Treatment/Plaquenil -, Plaquenil User Reviews for Sjogren's Syndrome at Hydroxychloroquine precautionsPlaquenil dental contraindications Hydroxychloroquine Plaquenil, a drug designed to treat malaria, is often helpful in treating Sjogren's syndrome. Drugs that suppress the immune system, such as methotrexate Trexall, also might be prescribed. Sjogren's syndrome - Diagnosis and treatment - Mayo Clinic. How does Plaquenil work? - Sjogren's Syndrome Support.. Conquering Sjogren's Plaquenil. Toothpastes and mouth rinses developed specifically for dry mouth may help. If replacing moisture does not relieve dryness, your doctor may prescribe a medication to stimulate your salivary glands to produce more saliva. Two drugs, pilocarpine Salagen and cevimeline Evoxac, are approved for dry mouth associated with Sjögren’s syndrome. Sjogren's Syndrome Support Group Sjogren's syndrome is an autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva. It also associated with rheumatic disorders such as rheumatoid arthritis, and it is rheumatoid factor positive in 90 percent of cases. Jun 16, 2016 Thanks for the response. The thing is I have not been diagnosed with Sjogren's yet. As I understand taking Plaquenil and seeing if it helps are a part of diagnosis. What makes me unwilling to take the risk, however small it may be, is that I only seem to have two symptoms.