It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Hydroxychloroquine and peripheral neuropathy Plaquenil causes skin rash Chloroquine hydrochloride injection Hydroxychloroquine and white spots on skin Transznamic acid is to make me clot during period so as to reduce the ehavy bleeding i get due to endometriois,fibroids.i take it 1st 4 days of period. it stops me bleeding for 2 weeks brings it down to 4 to 5 days instead. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine If patients do not respond to a 4-week trial of a proton-pump inhibitor or if there are signs of gastrointestinal bleeding, then an endoscopy procedure is recommended. Delayed gastric emptying often causes early satiety, aggravation of GERD, anorexia, or the sensation of bloating. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine internal bleeding Blood thinners can cause internal bleeding, Hydroxychloroquine Side Effects Common, Severe, Long Term. Chloroquine based chalcone Stomach bleeding and ulcers can become life threatening, so if you take aspirin or have aspirin-sensitive asthma or allergic reactions to aspirin, you should not take Celebrex. Other Precautions You may not be able to take an antidepressant such as Cymbalta, Prozac or Paxil while taking Celebrex as this may lead to complications, such as bruising or bleeding easily. Can You Take Other Pain Meds Along With Celebrex? Healthfully. My Approach to the Treatment of Scleroderma. Injectable bandage targets fatal internal bleeding. Losartan/hydrochlorothiazide is used to treat high blood pressure. It’s given when one drug isn’t enough to lower your blood pressure. This drug is also used to reduce the risk of stroke in people. Answer. Plaquenil does not need to be stopped for surgery so it can be restarted after the procedure. Although in studies Celebrex does not cause increased bleeding, unilke other older NSAIDs, some surgeons still advise to stop it to be safe. In general, Celebrex can be restarted the day after the procedure once the risk of bleeding is over. Unlike conventional bleeding which is out from the wound in the surface of the body and can be recognized easily, internal bleeding is bleeding happening inside the body in the tissue, organ or chamber, which is very difficult to identify without examination methods and certain diagnosis.