Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Plaquenil skin rash side effects Hydroxychloroquine mechanism rheumatoid arthritis Sometimes these manifestations can be linked to more serious lenticular, optic nerve or retinal findings, and this should be reported to the patient’s primary care physician in a timely manner. Report ocular side effects to the National Registry of Drug-Induced Ocular Side Effects at 1. Hollander DA, Aldave AJ. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Side effects of plaquenil on the cornea Plaquenil Indications, Side Effects, Warnings -, Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Chloroquine mnemonicPlaquenil after gastric sleeveEye exam plaquenilChloroquine prophylaxis dosage Serious Side Effects of Plaquenil. If you are taking Plaquenil long-term, such as for an autoimmune condition, your doctor should regularly check you for potential serious side effects. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Plaquenil Side Effects on Your Eyes and Vision. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Plaquenil is an extremely safe medication but retinal and corneal side effects are possible. Unfortunately, the retinal side effects are largely irreversible and can lead to vision loss. So, it is critical to detect early retinal toxicity in the hopes of limiting the extent of visual loss. Ask questions about non-ocular side effects as well. Only two third of patients comply with therapy, and most non-adherence to therapy are in patients under 80 kilograms in weight, likely because of an increased incidence of side effects. Common, nonocular, side effects of chloroquine and hydroxychloroquine include pruritus, headaches.