It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Chloroquine hydrochloride solubility Plaquenil avoid Plaquenil and alcohol interaction Apr 14, 2007 Third, apart from its direct effects on SLE activity, hydroxychloroquine seems to protect against thrombotic events and has a beneficial effect on lipid profiles, which might help reduce the high cardiovascular risk of SLE patients underlined by D'Cruz and colleagues. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Hydroxychloroquine and chloroquine are medications traditionally prescribed to prevent or treat malaria infections. In certain countries and parts of the world where malaria is still present, a person can easily catch malaria from a seemingly insignificant mosquito bite. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine and sle Plaquenil hydroxychloroquine sulfate dosing, indications., Hydroxychloroquine Oral Uses, Side Effects, Interactions. Can plaquenil cause restless leg syndromeAralen genericoUrinary side effects of hydroxychloroquine2016 ophthalmology journal hydroxychloroquineEye plaquenil screeniing Antimalarial therapy such as hydroxychloroquine in systemic lupus erythematosus SLE has documented benefit for reducing disease activity, improving survival, and reducing the risk of SLE-related thrombosis and myocardial infarction. Hydroxychloroquine in systemic lupus erythematosus SLE. What Is the Difference between Hydroxychloroquine and.. Hydroxychloroquine Plaquenil. Hydroxychloroquine, an antimalarial drug, is traditionally used in the treatment of SLE. Its effectiveness in treating APS has been previously questioned. In vitro and in vivo studies showed a beneficial effect of hydroxychloroquine on thrombosis 121–124. Hydroxychloroquine is used to treat discoid lupus erythematosus DLE or systemic lupus erythematosus SLE or lupus. It is also used to treat acute and chronic rheumatoid arthritis. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms Tablet; Before Using Malaria. PLAQUENIL is indicated for the treatment of uncomplicated malaria due to P. falciparum, P. malariae, P. ovale, and P. vivax. PLAQUENIL is indicated for the prophylaxis of malaria in geographic areas where chloroquine resistance is not reported.