Chloroquine mechanism malaria

Discussion in 'Canadian Pharmaceuticals Online' started by borrex, 28-Feb-2020.

  1. Head__Hunter Well-Known Member

    Chloroquine mechanism malaria


    Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take chloroquine with all of your drugs and health problems.

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    Chloroquine, or hydroxychloroquine, has been used to treat malaria since 1944. It can be given before exposure to malaria to prevent infection, and it can also be given as treatment afterward. There are only a few places left in the world where. chloroquine is still effective including parts of Central America and the Caribbean. CDC keeps track of all the places in the world where malaria transmission occurs and which malaria. drugs that are recommended for use in each place. The clinical usefulness of chloroquine, and in some recent cases of quinine as well, has been much reduced by the evolution and spread of chloroquine resistant malaria parasites. The mechanism of resistance involves a reduced accumulation of the drug, although again the mechanism involved is controversial.

    For all uses of chloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor.

    Chloroquine mechanism malaria

    Aralen Chloroquine Uses, Dosage, Side Effects., Medicines for the Prevention of Malaria While Traveling.

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  4. Resistance to chloroquine of malaria strains is known to be associated with a parasite protein named PfCRT, the mutated form of which is able to reduce chloroquine accumulation in the digestive vacuole of the pathogen.

    • On the Mechanism of Chloroquine Resistance in Plasmodium..
    • Chloroquine mechanism of drug action and resistance in..
    • Chloroquine - FDA prescribing information, side effects..

    Uses of Chloroquine It is used to treat or prevent malaria. It is used to treat a type of bowel infection. It may be given to you for other reasons. Chloroquine is an aminoquinoline used for the prevention and therapy of malaria. It is also effective in extraintestinal amebiasis and as an antiinflammatory agent for therapy of rheumatoid arthritis and lupus erythematosus. Chloroquine is an antimalarial and amoebicidal drug. The drug possesses antimalarial actions and exerts a beneficial effect in lupus erythematosus chronic discoid or systemic and acute or chronic rheumatoid arthritis. The precise mechanism of action is not known. Indication • Malaria Vivax malaria • Amoebic liver abscess

     
  5. kastorka87 User

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Antimalarials in pregnancy and lactation MDedge ObGyn Chloroquine - Safe In Breastfeeding Should I Be Taking Aspirin While I’m Breastfeeding?
     
  6. Prosvet Well-Known Member

    The following article looks at the medicinal chemistry of antimalarial drugs. Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs Structure Activity Relationship of CHLOROQUINE Quinine Uses, Actions, & Side Effects Britannica
     
  7. grig User

    Post-exposure Chloroquine Prophylaxis COVID19 The key with this kind of treatment is to try and prevent cells being infected in the first place so that only mild disease occurs, preventing hospitalisation. Because Chloroquine is cheap, abundant and low risk for short term dosage, it would be ideal as a single pill/weekly dose application to all contacts or people with cold like symptoms.

    WHO Model Prescribing Information Drugs Used in Parasitic.