Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine with requip Areas with chloroquine or mefloquine resistance Chloroquine adme Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. Chloroquine further supports this mechanism by blocking utilisation of extracellular cholesterol by neutralising the lysosome, thereby rendering cancer cells dependent on the biosynthesis pathway to maintain cellular and lysosomal membrane cholesterol homeostasis and lysosomal membrane integrity. Chloroquine is the active ingredient in one of the top selling medication for malaria prevention, Aralen Phosphate. Chloroquine is one of the most effective medicines to prevent and treat malaria and it is used all over the world! Chloroquine is also marketed as Aralen Phosphate, and Aralen Hydrochloride. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Chloroquine cholesterol Inhibition of cholesterol metabolism underlies synergy., The Chloroquine Story in Cancer Continues In the Pipeline Novo chloroquine 250 mgSide effects of plaquenil pmsChloroquine phosphate casHydroxychloroquine sulfate more likely to get sickPlaquenil for lupus mechanism If you have psoriasis, chloroquine Aralen and hydroxychloroquine Plaquenil can cause problems. Other Medicines That Might Trigger a Flare A few other drugs to discuss with your doctor include Drugs & Medications That Can Trigger Psoriasis Flare-Ups. Chloroquine. Hydroxychloroquine Uses, Dosage & Side Effects -. Chloroquine is a medication prevent or to treat malaria, a disease caused by parasites. This medicine works by interfering with the growth of parasites from the human body’s red blood cells. Parasites that cause malaria enter the body via the bite of a mosquito. Temozolomide, sirolimus and chloroquine is a new therapeutic combination that synergizes to disrupt lysosomal function and cholesterol homeostasis in GBM cells Sanford P. C. Hsu, John S. Kuo, Hsin Chien Chiang, Hsin Ell Wang, Yu Shan Wang, Cheng Chung Huang, Yi Chun Huang, Mau Shin Chi, Minesh P. Mehta, Kwan Hwa Chi Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus.