I also have been having unexplained swelling of my tongue, wrists, bottom of my feet and lip, spreading up in my cheek. Now my wife and i are very concerned and planning on going to see my doctor soon. I know it isn't allergies because I have kept a diary and there is no pattern as in your case I too would like some help in clarifying it. Eye exam for plaquenil Plaquenil cdc Swelling; trouble breathing ; If you develop these symptoms, call 911 or go to the nearest emergency room. Don’t take this drug again if you’ve ever had an allergic reaction to it. The hallmark picture of a typical lupus patient is one who comes in with a malar rash a dark reddish, “butterfly” rash or discoid lesions across the face,” he says. But other typical symptoms include joint pain, joint swelling, photosensitivity, headaches, nausea, fatigue and/or chronic low-grade fever. Numbness in my fingers, hands and pain up my arm to my elbow. But this would come and go, the swelling in my fingers would decrease through out the day. Well it's never that easy, since then I've had swollen knees where I couldn't even bend my knees, felt like bags of milk in my knees. Feet and ankle pain, like every bone was broken. I have tried to put all of this on food, detergent, allergies, etc.. Currently as I'm writing this am having the same symptoms you describe under my feet, it started about 4-5 months ago, were swelling of the lips, tongue and side of the mouth swells up, and most recently started to get the swelling under my feet with the same description you noted, also my hand and my wrist, all these caused an itching feeling and felt very warm to touch and is difficult to walk on. I ate a chocolate apricot cake, something I have never had. The same exact thing that you have described has happened to me and much more regularly recently. my wife and i thought it maybe caused due to an allergic reaction, i did go to en allergist and after various tests he indicated that i am not allergic to anything. My foot had this crazy itch (left foot) and then I was walking and it felt like the outside of my foot had like gum or something stuck to the bottom of it. I have been told it is stress, but I don't feel stressed. Plaquenil lip swelling Giving 'em Lip - Sjogren's, Salivary Glands, and More Fun, Lid Swelling Linked to Lupus? Is plaquenil toxic to the liverPlaquenil adverse effects Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have Plaquenil Uses, Dosage & Side Effects -. Plaquenil hair loss nioxin review Sjogrens. RA patient with swollen lips" Rheumatoid Arthritis Community.. Plaquenil and Lip swelling - from FDA reports Summary Lip swelling is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Benlysta, and have High blood pressure. Mouth sores related to lupus most often present on the roof of the mouth but can also occur on the gums, inside of the cheeks, and the lips. These sores are usually painless although some may experience pain, which makes them different from other types of mouth sores or ulcers like canker sores. What are the possible side effects of hydroxychloroquine Plaquenil, Plaquenil Sulfate, Quineprox? Get emergency medical help if you have signs of an allergic reaction hives; difficulty breathing; swelling of your face, lips, tongue, or throat.