Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil pill image Plaquenil and rapid heartbeat Chloroquine is also used to treat infection caused by a different type of parasite ameba by killing the ameba. How to use Chloroquine Phosphate. Take this medication by mouth. What are anti-malarial drugs, and why are they used to treat lupus? Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Why is chloroquine used to treat lupus Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Treating Lupus with Anti-Malarial Drugs Johns Hopkins. Plaquenil 200 in pregnancyPlaquenil crpEileen white chloroquine The antimalarial quinine was first used to treat cutaneous lupus in 1834. Subsequent reports in 19 showed good results with another quinine-like drug in the treatment of both discoid and subacute cutaneous lupus. In 1941, discoid lupus patients were treated successfully with Atabrine. Drug spotlight on hydroxychloroquine Lupus Foundation of America. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Why are treatments that were developed for malaria now.. Chloroquine Aralen is used for preventing and treating malaria and amebiasis, an infection of the intestines caused by a parasite. Why are antimalarial drugs specifically chloroquine and hydroxychloroquine used to treat Lupus? I know in which cases they're used. I mean, what's the mechanism that makes them useful against this disease? I spent a summer on Plaquenil, but had. The use of 4-aminoquinolines is generally considered contraindicated in the presence of retinal or visual field changes, whether attributable to 4-aminoquinoline compounds or to any other etiology. However, in the treatment of acute attacks of malaria caused by susceptible strains of plasmodia, these agents may be considered if potential.