Hydroxychloroquine (Plaquenil®) has received little attention in Crohn’s disease (CD). Many anti-inflammatory medications used for rheumatoid arthritis have been applied to inflammatory bowel disease (IBD) therapy. Chloroquine prostate cancer How many people survived malaria with chloroquine Bowel disorders often affect your small intestine. Learn about the symptoms and treatment options for common types, such as irritable bowel syndrome. READ MORE. Ileus. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. I am not familiar with Gabapentin. I am very familiar with Plaquenil, and Plaq does cause some tummy discomfort at the start. It can cause loss of appetite, diarrhea, and accompanying gas and intestinal noises. You can get some OC Immodium AD to try and combat the lower bowel issues. Furthermore it has remained effective for a number of patients for many years (Personal Communication, Lloyd Mayers, MD, 2010). The mechanism of actions that might apply to IBD includes inhibition of T-cells and intracellular stabilization of intracellular inflammation and the immune cascade. Plaquenil and intestinal problems Plaquenil and stomach issues." Lupus Community - Support Group, Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs Hydroxychloroquine usmlePlaquenil toxicity macular octDoes plaquenil treat rhupus Re Prednisone, plaquenil and constipation. I haven't experienced any problems with constipation while on prednisone and plaquenil. I had a lot of bowel trouble before I was DXD though, which may be why I am not having problems now, could be that the drugs just evened me out so to speak. Immune & Autoimmune - Lupus Prednisone, plaquenil and. Stomache Gas from Plaquenil or Gabapentin" Lupus Community - Support.. Plaquenil and diarrhea -. Hydroxychloroquine Plaquenil® has received little attention in Crohn’s disease CD. 1 This anti-malarial agent is an older disease-modifying anti-rheumatic drug and is used by rheumatologists for patients who try and fail or fear trying immunomodulator and biologic therapy. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Nov 28, 2010 When I first started taking Plaquenil, it was a little hard on my stomach, but I just make sure I eat a banana or something before I take it, and I have no problems. Sometimes, I think my rheumy is just sitting back waiting for something else to pop up. He has really helped me with medication, though. My NP thinks I have seronegative RA.